MDiNE: a model to estimate differential co-occurrence networks in microbiome studies

摘要

Motivation: The human microbiota is the collection of microorganisms colonizing the human body, and plays an integral part in human health. A growing trend in microbiome analysis is to construct a network to estimate the cooccurrence patterns among taxa through precision matrices. Existing methods do not facilitate investigation into how these networks change with respect to covariates.