Effect of Interferon alfa-2a Treatment on Adaptive and Innate Immune Systems in Patients With Behcet Disease Uveitis

Albayrak Ozgur; Oray Merih; Can Fusun; Kirimli Gunay Uludag; Gul Ahmet; Tugal-Tutkun Ilknur; Onal Sumru

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Effect of Interferon alfa-2a Treatment on Adaptive and Innate Immune Systems in Patients With Behcet Disease Uveitis

机译：干扰素ALFA-2A治疗对Behcet病葡萄膜炎患者适应性和先天免疫系统的影响

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PURPOSE. To investigate the effect of interferon alfa-2a on T regulatory (Treg) cells, T helper 17 (Th17) cells, and expression of Toll-like receptors (TLRs) in Behcet disease (BD) patients with uveitis.

机译：目的。为了探讨干扰素ALFA-2A对T型调节（TREG）细胞，T辅助17（TH17）细胞的影响，以及在葡萄膜炎的患者中的Toll样受体（TLRS）的表达和表达。

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来源
《Investigative ophthalmology & visual science》 |2019年第1期|共12页
作者
Albayrak Ozgur; Oray Merih; Can Fusun; Kirimli Gunay Uludag; Gul Ahmet; Tugal-Tutkun Ilknur; Onal Sumru;
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作者单位

Koc Univ Sch Med Dept Med Microbiol Istanbul Turkey;

Istanbul Univ Dept Ophthalmol Istanbul Fac Med Istanbul Turkey;

Koc Univ Sch Med Dept Med Microbiol Istanbul Turkey;

Koc Univ Hosp Dept Ophthalmol Istanbul Turkey;

Istanbul Univ Div Rheumatol Dept Internal Med Istanbul Fac Med Istanbul Turkey;

Istanbul Univ Dept Ophthalmol Istanbul Fac Med Istanbul Turkey;

Koc Univ Sch Med Dept Ophthalmol Davutpasa Cad 4 TR-34010 Istanbul Turkey;

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原文格式 PDF
正文语种 eng
中图分类眼科学;
关键词
interferons; Behcet disease; uveitis; adaptive; innate;

机译：干扰素;Behcet病;葡萄膜炎;自适应;天生;

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专利

1. Effect of Interferon alfa-2a Treatment on Adaptive and Innate Immune Systems in Patients With Behcet Disease Uveitis [J] . Albayrak Ozgur, Oray Merih, Can Fusun, Investigative ophthalmology & visual science . 2019,第1期

机译：干扰素ALFA-2A治疗对Behcet病葡萄膜炎患者适应性和先天免疫系统的影响
2. INTERFERON ALFA-2A IN TREATMENT OF REFRACTORY UVEITIS ASSOCIATED BEHCET'S DISEASE: A SINGLE-CENTRE EXPERIENCE iN CHINA [J] . Zheng W., Shi J., Zhao C., Clinical and experimental rheumatology . 2016,第6Suppla102期

机译：干扰素Alfa-2a治疗难治性葡萄膜炎相关的Behcet病：在中国的单中心经验
3. Low-dose interferon alfa-2a therapy in severe uveitis associated with Behcet disease. [J] . Onal S, Kazokoglu H, Direskeneli H American Journal of Ophthalmology: The International Journal of Ophthalmology . 2009,第6期

机译：小剂量干扰素α-2a治疗与贝塞特病相关的严重葡萄膜炎。
4. Patients with HCV/HIV Co-infection Achieving a Sustained Virological Response Following HCV Treatment with Peginterferon alfa-2a (PEGASYS) plus Ribavirin (COPEGUS) have Improved Health Related Quality of Life [C] . D.T. Dieterich, M. Rodriguez Torres, J.K. Rockstroh International AIDS Conference . 2004

机译：HCV / HIV的患者在用Peginterferon Alfa-2a（Pegasys）加上利巴韦林（Copegegs）后HCV治疗后实现持续的病毒学反应，具有改善的健康相关的生活质量
5. Modulation of Type-I interferon mediated immune response: A novel innate immune evasion strategy of equine herpesvirus 1 [D] . Sarkar, Sanjay 2014

机译：I型干扰素介导的免疫反应的调节：马疱疹病毒1的新型先天免疫逃避策略。
6. Clinical Experience of Interferon Alfa-2a Treatment for Refractory Uveitis in Behçets Disease [O] . Ji-Youn Park, Yoo-Ri Chung, Kihwang Lee, 2015

机译：干扰素Alfa-2a治疗Behçet病顽固性葡萄膜炎的临床经验
7. Effect of Interferon Alfa-2a on Peripheral Blood CD4+CD25+ T Regulatory Cells in Patients with Behcet Uveitis: Preliminary Study [O] . Aylin Koc 2015

机译：干扰素Alfa-2a对Behcet葡萄膜炎患者外周血CD4 + CD25 + T调节细胞的影响：初步研究

Effect of Interferon alfa-2a Treatment on Adaptive and Innate Immune Systems in Patients With Behcet Disease Uveitis

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