Palladium (II) complexes based on Schiff base ligands derived from ortho-vanillin; synthesis, characterization and cytotoxic studies

摘要

Graphical abstractDisplay OmittedHighlights?Novelortho-vanillin based N, O donor Schiff bases.?Highly stable four coordinate palladium complexes derived from these novel ligands.?Higher anti-proliferative activity on three cancerous cell lines thancis-platin.Abstract6-Methoxy-2-[(E)-Aryliminomethyl]-phenol (Aryl?=?Phenyl; 2,6-dimethyl; 2,6-diisopropylphenyl; 2,6-dichlorophenyl), comprising L1–L4ligands, and palladium complexes [Pd(Ln)2, n?=?1–4] have been synthesized. The geometries of the [Pd(Ln)2