Effects of Ivabradine on left ventricular function in patients with ischemic heart disease

摘要

With great interest, we read the recent article entitled with "Ivabradine significantly improves cardiac function in patients with ischemic heart disease: A meta-analysis of randomized controlled trials" [1 ]. The authors included 7 randomized controlled trials with a total of 1542 patients for meta-analysis and concluded that Ivabradine significantly improved cardiac function in patients with ischemic heart disease. In our opinion, this is an interesting manuscript analyzing the effects of Ivabradine on left ventricular function in patients with ischemic heart disease. To enrich the study conducted by Peng et al., we have several comments as follows: Firstly, the authors performed an extensive search from 6 databases by using the following keywords/Medical Subject Headings: "Ivabradine plus myocardial infarction or angina or ischemic cardiomyopathy or heart failure or coronary artery disease or ischemic heart disease". The search was restricted to "randomized controlled trial".