Gender differences and clinical outcome in patients undergoing trans-femoral aortic valve implantation

摘要

In contrast to other interventions in cardiovascular medicine in which the impact of gender on outcomes has been well-investigated, there is still controversy regarding the effect of gender on the clinical results of TAVI. Studies designed to examine this issue vary in their cohort size, duration of follow-up, implantation technique, type of prosthetic valve, and the adjustment for baseline clinical features.We evaluated the gender-related differences in regard to baseline characteristics and clinical outcomes in a cohort of high-risk aortic stenosis (AS) patients undergoing trans-femoral TAVI. The primary endpoints were 30-day all-cause mortality, survival as measured by Cox regression model, combined 30-day complication rate and procedural success as defined by the VARC (the Valve Academic Research Consortium).