Synthesis, Characterization, Antimicrobial and Cytoxic Activities of Copper(II) Isocynate Complex of Schiff Base

摘要

In this paper, Schiff base ligand using acetyl acetone, o-phenylenediamine and salicylaldehyde and its copper complex have been synthesized using self-assembly method. The ligand and its copper(II) complex were characterized by spectroscopic techniques. The antimicrobial studies are carried out for ligand and its copper complex, which confirmed that copper complex does not show any activity against bacteria as well as fungal organisms. However, the cytotoxic studies showed that copper complex has good anticancer activity against MCF-7 (breast cancer) cell line.