Evidence-based review of current treatment options for chronic kidney disease-associated anemia in diabetes

摘要

Purpose of review: Chronic kidney disease is a major cause of morbidity and mortality in patients with diabetes. Chronic kidney disease is associated with multiple co-morbidities, and anemia is one of the most frequent. Anemia leads to reduced quality of life and many hemodynamic changes that may impact the outcome of diabetic patients with chronic kidney disease. Anemia is readily identified and treated in diabetic patients with chronic kidney disease. Recent findings: This past year has been marked by many studies highlighting the negative impact of chronic kidney disease on individuals with diabetes, specifically that it is associated with excess cardiovascular disease and mortality. Studies have detailed the frequency and severity of anemia in diabetic patients. Many studies have demonstrated the efficacy of treatment for anemia in diabetic patients and suggested benefits beyond correction of the hematocrit. Summary: Effective options are available for the correction of anemia in diabetic patients with chronic kidney disease. Early, aggressive and effective treatment will improve the quality of life and can possibly reduce morbidity and mortality in patients with diabetes and chronic kidney disease. 2006 Lippincott Williams & Wilkins.