Prevention of type 2 diabetes and its macrovascular complications: whom, when, and how should we treat?

摘要

Numerous studies suggest that treatment directed at the metabolic syndrome, which often antedates type 2 diabetes and IGT should be considered as a means of preventing both these disorders and the cardiovascular disease with which they are often associated. Available evidence suggests that diet, exercise, and other treatments that activate AMPK could be useful in diminishing cardiovascular disease risk in these individuals, as well as retarding the development of diabetes.