Microchip-based high-throughput screening analysis of combinatorial libraries

摘要

In recent years, there have been significant advances in biochemical assay miniaturization and integration of microchip-based technologies with combinatorial library screening for high-throughput and large-scale applications. Small-molecule microarrays, protein arrays and cell-based arrays and conventional DNA arrays as well as microfluidic approaches in HTS are discussed in this review.