Tara tannin as active ingredient in electrospun fibrous delivery system

摘要

This study evaluated the releasing performance of tara tannin, a cocktail of plant polyphenols, incorporated in submicron fiber, produced by the electrospinning process. Polylactic acid was used as a polymer matrix that carried two loading levels of tara tannin, 14.3 and 22.3% dry weight in the final product. The fiber diameter of composite fibers was in the range 500-700 nm. The release of tara tannin was controlled by material attachment as there was no evidence of chemical bonding between materials. This was further confirmed by FTIR and DSC. From the five combinations of acid that were presented in tara tannin, galloylquinic acid, with the smallest molecular weight composition, was released in the largest proportion (%molar) and exhibited antioxidant activity. This was confirmed by 2,2-diphenyl-1-picrylhydrazyl assay and HPLC-MS analyses. (c) 2016 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2016, 133, 43646.