Simultaneous multiple sample light scattering for analysis of polymer solutions

摘要

An instrument for performing Simultaneous Multiple Sample Light Scattering (SMSLS) is introduced, which allows multiple, independent polymer samples to be analyzed simultaneously. Three demonstrations of SMSLS capabilities are made; proof of the SMSLS ability to make absolute Rayleigh scattering ratio measurements on well-defined standards, the monitoring of a biopolymeric degradation process (hyaluronate degradation using hyaluronidase), with subsequent determination of the Michaelis-Menten constant, and an aggregation process (low concentration gelatin solutions). It is hoped that SMSLS will become a valuable tool for rapid screening and characterization of both equilibrium properties and nonequilibrium processes in polymer solutions. (C) 2004 Wiley Periodicals, Inc. [References: 40]