High expression of MAGE-A4 and MHC class I antigens in tumor cells and induction of MAGE-A4 immune responses are prognostic markers of CHP-MAGE-A4 cancer vaccine

Saito Takuro; Wada Hisashi; Yamasaki Makoto; Miyata Hiroshi; Nishikawa Hiroyoshi; Sato Eiichi; Kageyama Shinichi; Shiku Hiroshi; Mori Masaki; Doki Yuichiro

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High expression of MAGE-A4 and MHC class I antigens in tumor cells and induction of MAGE-A4 immune responses are prognostic markers of CHP-MAGE-A4 cancer vaccine

机译：MAGE-A4和MHC I类抗原在肿瘤细胞中的高表达和MAGE-A4免疫应答的诱导是CHP-MAGE-A4癌症疫苗的预后标志物

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Purpose: We conducted a cancer vaccine clinical trial with MAGE-A4 protein. Safety, clinical response, and antigen-specific immune responses were analyzed and the prognostic factors by vaccination were investigated.

机译：目的：我们使用MAGE-A4蛋白进行了癌症疫苗临床试验。分析安全性，临床反应和抗原特异性免疫反应，并研究疫苗接种的预后因素。

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《Vaccine》 |2014年第45期|共7页
作者
Saito Takuro; Wada Hisashi; Yamasaki Makoto; Miyata Hiroshi; Nishikawa Hiroyoshi; Sato Eiichi; Kageyama Shinichi; Shiku Hiroshi; Mori Masaki; Doki Yuichiro;
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正文语种 eng
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关键词
CT antigen; MAGE-A4; Cancer vaccine; Prognosis; MHC; Monitoring;

机译：CT抗原;MAGE-A4;癌症疫苗;预后;MHC;监测;

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1. High expression of MAGE-A4 and MHC class I antigens in tumor cells and induction of MAGE-A4 immune responses are prognostic markers of CHP-MAGE-A4 cancer vaccine [J] . Saito Takuro, Wada Hisashi, Yamasaki Makoto, Vaccine . 2014,第45期

机译：MAGE-A4和MHC I类抗原在肿瘤细胞中的高表达和MAGE-A4免疫应答的诱导是CHP-MAGE-A4癌症疫苗的预后标志物
2. Cancer/testis antigen MAGE-A4 expression pattern differs in epithelial skin tumors of organ-transplant recipients and immunocompetent patients. [J] . Muehleisen B, Schaerer L, Dummer R, Journal of cutaneous pathology . 2007,第1期

机译：癌症/睾丸抗原MAGE-A4表达模式在器官移植受体和免疫功能正常的患者的上皮性皮肤肿瘤中有所不同。
3. Expression and Possible Prognostic Role of MAGE-A4, NY-ESO-1, and HER-2 Antigens in Women with Relapsing Invasive Ductal Beast Cancer: Retrospective Immunohistochemical Study [J] . Bandi? Daniela, ?ovi? Dinko, Giulio C., Croatian medical journal . 2006,第1期

机译：MAGE-A4，NY-ESO-1和HER-2抗原在复发性导管癌患者中的表达及其可能的预后作用：回顾性免疫组织化学研究
4. INDUCTION OF ANTIGEN-SPECIFIC IMMUNE RESPONSES BASED ON CHEMICAL MODIFICATION OF ANTIGEN PROTEINS TARGETING TO ANTIGEN PRESENTATING CELLS [C] . Yasuomi Yamasaki, Tomoko Ikenaga, Yoshinobu Takakura Proceedings of the 29th Annual Meeting of the Controlled Release Society . 2002

机译：基于针对抗原预增敏细胞的抗原蛋白的化学修饰，诱导抗原特异性免疫反应
5. I: Delivery of Carbohydrate Antigens by Glycopolymers as Potential Anti-cancer Vaccines; II: A Study of the Impacts of Valency and Density on Immune Response Against a Tumor Associated Carbohydrate Antigen [D] . Qin, Qian 2019

机译：I：糖聚合物作为潜在的抗癌疫苗传递碳水化合物抗原； II：价和密度对针对肿瘤相关碳水化合物抗原的免疫反应的影响的研究
6. Expression and Possible Prognostic Role of MAGE-A4 NY-ESO-1 and HER-2 Antigens in Women with Relapsing Invasive Ductal Beast Cancer: Retrospective Immunohistochemical Study [O] . Daniela Bandić, Antonio Juretić, Božena Šarčević, 2006

机译：复发性导管癌患者中MAGE-A4NY-ESO-1和HER-2抗原的表达及其可能的预后作用：回顾性免疫组织化学研究
7. シュヨウ　サイボウ　ノ　ＭＡＧＥ－Ａ４・ＭＨＣ　ｃｌａｓｓＩ　コウゲン　コウハツゲン　ト　ＭＡＧＥ－Ａ４　トクイテキ　メンエキ　ハンノウ　ノ　ユウドウ　ハ　ＣＨＰ－ＭＡＧＥ－Ａ４　ガン　ワクチン　ノ　ヨゴ　マーカー　ト　ナル [O] . 西塔拓郎, サイトウタクロウ 2017

机译：Shuyou Cybo-no MAGE-A4 / MHC I类小原健人MAGE-A4

High expression of MAGE-A4 and MHC class I antigens in tumor cells and induction of MAGE-A4 immune responses are prognostic markers of CHP-MAGE-A4 cancer vaccine

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