Strategy for rhinosinusitis confirmed

摘要

FRESH evidence to support National Institute for Health and Clinical Excellence recommendations to avoid or delay antibiotic treatment for patients with acute rhinosinusitis has emerged from a study published online in JAMA (15 February 2012). Patients with acute rhinosinusitis who received a 10-day course of amoxicillin reported no reduction in symptoms after three days of treatment compared with those who took placebo. In the US study, 166 adults with uncomplicated acute rhinosinusitis were randomised to receive amoxicillin (l,500mg/day) or placebo for 10 days. Patients with symptoms indicative of serious complications were excluded.