Small benefit for antibiotics in sinusitis but consider risks

摘要

Antibiotics provide a small benefit in acute sinusitis,but this must be weighed against potential adverse effects for individuals and the population as a-whole,the authors of a Cochrane review conclude(Cochrane Database of Systematic Reviews 2008;issue 2).The review uncovered five studies involving 631 participants that showed a slight statistical difference in favour of antibiotics in primary care treatment of uncomplicated acute sinusitis,compared with placebo(pooled relative risk 0.66,95 per cent confidence interval 0.44-0.98).