Metformin safe and effective to treat diabetes that develops in pregnancy,say researchers

摘要

Metformin is a safe and effective treatment for women with gestational diabetes mellitus,a study published this week in The New England Journal of Medicine confirms(2008;358:2003).Researchers randomly assigned 751 women with gestational diabetes at 20 to 33 weeks of pregnancy to receive open treatment with metformin(with supplemental insulin if required)or insulin.They found that metformin,alone or in conjunction with supplemental insulin,was not associated with an increase in neonatal complications compared with insulin.