Buccal route is an alternative for treating acute seizures in children

摘要

Buccal midazolam is more effective than rectal diazepam for treating acute seizures in children,a UK study has shown (Lancet 2005;366:205).The trial,based at Alder Hey Children's Hospital,Liverpool,Derbyshire Children's Hospital,Birmingham Children's Hospital and Queen's Medical Centre,Nottingham,compared the treatments across 219 episodes in 177 children aged over six months who presented to hospital with seizures and could not be treated with intravenous drugs.