Immunoadsorption for haemolytic uraemic syndrome.

摘要

In May, 2011, an outbreak of enterohaemorrhagic Escherichia coli (EHEC) 0104:H4 occurred in Germany. On July 27, the outbreak was over but had by then caused 3469 cases of EHEC infection and 852 cases of haemolytic uraemic syndrome. 50 patients died, including 18 patients with EHEC and 32 with haemolytic uraemic syndrome.'The strain of Ecoli was unusual in that it mainly affected adults (89% of patients, with a median ageof 43years) and women (68%). 25%of cases of EHEC progressed to haemolytic uraemic syndrome, which was much higher than the 6% reported through active surveillance ofShiga-toxin(Stx) producing EHECO157in the USA.2 Although haemolytic uraemic syndrome chiefly affects the renal system, neurological complications can occur and are associated with high mortality.