Herpes in STAT1 deficiency

摘要

In July, 2011, a 47-year-old woman and her 16-year-old daughter presented to our services because of persistent and recurrent oral candidosis. The mother began experiencing genital candidosis at the age of 3 years and her nails became affected when she was 4 (see appendix). From the age of 5 years, she presented with herpetic vesicles two to four times per year, mainly affecting her face. She had chickenpox when she was 5 years old and 1 year later had shingles. At 21 years, she developed cutaneous herpes lesions over an 8x5 cm area on the right side of her face. At 30 years, she had another episode of shingles on her right trunk. At 45 years, retrosternal discomfort and pain on swallowing solid food developed.