Ageing faster with AIDS in Africa.

摘要

As the AIDS epidemic matures, evidence is emerging that poorly managed HIV infection exacerbates ageing diseases, leading to increased morbidity and mortality, and that exacerbated chronic diseases should now be considered AIDS-related. Cohort evaluations indicate that non-AIDS cancers, pulmonary diseases, intracranial haemorrhage, osteoporosis, and age-related blindness, which might previously have been considered of low importance due to low prevalence, are becoming major causes of reduced quality of life and causes of death. Thanks to antiretroviral therapy, a person diagnosed HIV-positive and aged 20 years in the developed countries can expect to be alive well into their sixties, and these settings are well equipped to deal with an ageing HIV-positive population with the availability of specialised care.