Tranexamic acid for trauma.

摘要

The CRASH-2 trial (July 3, p 23) showed reduced trauma mortality through the simple and cheap intervention of tranexamic acid, placing it into a growing list of options for managing the acute coagulopathy of trauma. This list includes fresh frozen plasma, cryoprecipitate, platelets, fibrinogen, thrombin, prothrombin complexes, recombinant factor Vila, and now tranexamic acid-all with varied levels of efficacy, but uncertain effectiveness.