Haemodialysis access via tissue-engineered vascular graft.

摘要

Todd McAllister and colleagues' Article (April 25, p 1440) on the use of autologous tissue-engineered vascular grafts in patients on haemodialysis is a seminal paper on the use of bioengineered tissue in clinical medicine. But we were somewhat surprised by the frequency of aneurysms or graft dilatations in this small cohort after a short time of use. We wonder whether there is a relation between the dilatation of the graft and the underlying kidney disease, in particular autosomal dominant polycystic kidney disease (ADPKD).