Bioengineered human skin from embryonic stem cells.

摘要

The therapevtic use of human embryonic stem cells (hESCs) is currently prevented by several important hurtles. These hurdles include the availabilty of well-characterised, appropriately monitored cell Iines that can be specified into the required Iineages repro-ducibly and efficiently, without resulting in tumour formation or eliciting an immune response resulting in rejection. However, recent progress has provided hope that these challenges are not insurmountable and might eventually result in the use of hESCs for regenerative therapies for various diseases, including spinal cord injury, Parkinson's disease,and majortissue deficits.