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首页> 外文期刊>The Lancet >A painless, swollen finger (for 20 years).
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A painless, swollen finger (for 20 years).

机译:无痛肿胀的手指(长达20年)。

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A 94-year-old woman was referred to a dermatology clinic with a painless, smooth, hard swelling over the proximal interphalangeal joint of her left little finger (figure). The swelling had been present for 20 years. We could see yellow-white material under the skin. The patient had similar changes over the metatarsal joints of her feet, with overlying ulceration. Skin biopsy and aspiration of joint fluid excluded calciphylaxis, and confirmed that the patient had urate deposits (tophi)-ie, gout. Microscopy with polarised light showed negatively birefringent urate crystals. The serum concentration of urate was 530 umol/L (normal concentration 60-360 mumol/L). We prescribed allopurinol. Gout mainly affects men, but this predominance is less pronounced among elderly people-in whom gout usually affects more than one joint, often affects the hand, and tends to develop gradually, with fewer acute attacks than in younger people. Nonetheless, painless gout is rare.
机译:一名94岁的妇女被转诊至皮肤科门诊,其左小指的近端指间关节无痛,光滑,硬肿(图)。肿胀已经存在了20年。我们可以看到皮下有黄白色的物质。病人的足tar骨关节有类似的变化,并有溃疡。皮肤活检和关节液抽吸排除了预防性除钙剂,并确认患者有尿酸盐沉积物(痛风石)。偏光显微镜显示负双折射尿酸盐晶体。尿酸盐的血清浓度为530 umol / L(正常浓度为60-360 mumol / L)。我们开了别嘌醇。痛风主要影响男性,但是这种情况在老年人中并不明显。在老年人中,痛风通常会影响多个关节,经常会影响手,并且会逐渐发展,急性发作的发生率比年轻人少。尽管如此,痛风仍很罕见。

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