Sequential regimens for Helicobacter pylori eradication

摘要

Triple therapy with clarithromycin and proton-pump inhibitors (PPI) is the recommended regimen for Helicobacter pylori eradication1 in Europe, the USA, and Canada. This treatment was first described by Italian researchers2 and has been the mainstay of therapy against H pylori for more than a decade. Eradication rates of overdyspepsia, less pathogenic strains of H pylori, or an increasing incidence of macrolide resistance