Compliance with osteoporosis therapy is the weakest link.

摘要

The lifetime risk for fragility fractures due to osteoporosis after the age of 50 years is about 50% in women and 20% in men.The resultant high morbidity, mortality, and economic costs for elderly people are well recognised, and have stimulated the development of effective interventions to reduce fracture risk. Despite these advances, however, two challenges have hindered reduction of this public-health burden. We need to better identify individuals with a high risk of fracture to target treatment more cost-effectively. We also need to ensure that patients take their treatment as prescribed (compliance) and for the recommended duration (persistence).