Definition of Insignificant Tumor Volume at Radical Prostatectomy

摘要

Clinically insignificant Gleason 6 (Grade Group 1) prostate cancer is sometimes defined as tumor volume less than 0.5cm3. Kryvenko and Epstein (page 1664) from Miami, Florida evaluated 439 radical prostatectomy specimens, and only 3.8% of those with a volume of less than 0.5cm3 and Gleason 6 cancer had extraprostatic extension or apical extension compared to 11.1% of those with a volume of 0.5 to 2.0 cm3.7