Re: Association of testosterone therapy with mortality, myocardial infarction, and stroke in men with low testosterone levels: Editorial comment

摘要

Editorial Comment: Another article that has fueled debate. The authors assessed the association between testosterone therapy and all cause mortality, myocardial infarction and stroke among male veterans to determine whether this association is modified by underlying coronary artery disease. This is a retrospective national cohort study of men with low testosterone levels (less than 300 ng/dl) who underwent coronary angiography in the Veterans Affairs (VA) system between 2005 and 2011. Primary outcome was a composite of all cause mortality, myocardial infarction and ischemic stroke. Among a cohort of men in the VA health care system who underwent coronary angiography and had low serum testosterone levels the use of testosterone therapy was associated with an increased risk of adverse outcomes.