The authors report that infants born with high grade vesicoureteral reflux and 3 findings have a less than 10% chance of having the reflux resolve before age 3 years. These findings are scinti-graphic renal abnormality, poor bladder emptying and breakthrough infection. Conversely in the absence of all 3 findings 90% of cases will resolve or improve to a low grade (I to II) by age 3 years. This observation confirms what many may know intuitively, which is that infants with high grade reflux who are least likely to have the condition resolve spontaneously are those with the most abnormal vesicoureteral junctions and associated congenital renal dysplasia.
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