Chains of Cobalt Doped Magnetosomes Extracted from AMB-1 Magnetotactic Bacteria for Application in Alternative Magnetic Field Cancer Therapy

摘要

We report the magnetic properties and heating efficiency of cobalt doped chains of magnetosomes extracted from magnetotactic bacteria for applications in alternative magnetic field cancer therapy. The changes of the magnetic properties of the chains of magnetosomes observed in the presence of cobalt are characterized by an enhancement of the magnetocrystal-line anisotropy from K_(eff)～12 KJ/m~3 in the absence of cobalt up to K_(eff)～104 Kj/m~3 in the presence of cobalt. We show that these changes are only observed for the magnetosomes organized in chains. Furthermore, the SAR of the extracted chains of magnetosomes mixed in solution and exposed to an oscillating magnetic field of field amplitude 80 mT and frequency 183 kHz is shown to increase from ～400 W/g_(Fe) for the undoped chains of magnetosomes up to ～500 W/g_(Fe) for the cobalt doped chains of magnetosomes.