Combination Therapeutic Approach for Asthma and Allergic Rhinitis

摘要

s (1981-2006) on the topics identified above were selected.Results: The pathophysiology of asthma and allergic rhinitis is a complex cascade of events and mono therapy with drugs, which inhibits synthesis and release of a mediator or blocks the receptors of respective mediators, does not result in complete relief in the symptoms. From several clinical trials it can be concluded that combination therapy with two or more drugs may provide additive or synergistic benefits in blocking pathophysiological endpoints and also complement each other by blocking abroad spectrum of inflammatory processes than that provided by either drug alone.Conclusion: From the available scientific data from clinical trials it can be concluded that combination therapeutic approach may be a viable option for the treatment of asthma and allergic rhinitis.