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Memory effects during the unbiased translocation of a polymer through a nanopore

机译:聚合物通过纳米孔的无偏位易位过程中的记忆效应

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摘要

Through a detailed Langevin dynamics simulation study, the role of memory effects during unbiased translocation is explored. Tests are devised to uncover the presence of memory effects by directly measuring forward/backward-correlated motion as well as the associated change in the dynamics. Conducting these tests at low and high viscosities, a range of behaviours across different time scales is revealed: short-time forward correlations at all viscosities, quasi-static behaviour at low viscosity, and long-time backward correlations at high viscosity. By applying these tests at different portions of the translocation process, these memory effects are also shown to vary as translocation proceeds. Combining this information with standard measurements, a physical picture of unbiased translocation as the diffusion of a local minimum is proposed.
机译:通过详细的兰格文动力学模拟研究,探讨了记忆效应在无偏位易位过程中的作用。通过直接测量向前/向后相关的运动以及动态相关的变化,设计了测试来发现记忆效应的存在。在低粘度和高粘度下进行这些测试,揭示了在不同时间范围内的一系列行为:所有粘度下的短时正向相关性,低粘度下的准静态行为以及高粘度下的长时间后向相关性。通过在易位过程的不同部分进行这些测试,这些记忆效应也会随着易位的进行而变化。将该信息与标准测量值相结合,提出了无偏差易位的物理图像,即局部最小值的扩散。

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