The Complete Genome of an Individual by Massively Parallel DMA Sequencing

摘要

Using massively parallel sequencing in picoliter reaction vessels, David Wheeler and colleagues have sequenced the genome of James D. Watson to 7.4-fold redundancy in two months at approximately one-hundredth of the cost of traditional capillary electrophoresis methods. This is the first genome to be sequenced by next-generation sequencing technologies.