Palladium-catalyzed decarboxylative ortho-acylation of N-nitrosoanilines with alpha-oxocarboxylic acids

摘要

A palladium-catalyzed efficient C-H acylation reaction of N-nitrosoanilines with alpha-oxocarboxylic acids has been developed. The reaction proceeded smoothly with potassium persulfate as the oxidant to afford acylated N-nitrosoanilines in moderate to good yields with a broad substrate scope and good regioselectivity. (C) 2016 Elsevier Ltd. All rights reserved.