Carbocatalysis: reduced graphene oxide-catalyzed Boc protection of hydroxyls and graphite oxide-catalyzed deprotection

摘要

A new metal-free method for O-Boc protection of alcohols and phenols was achieved with reduced graphene oxide (RGO) as an efficient and recyclable catalyst. Graphite oxide (GO) served as the catalyst for the deprotection of Boc group with methanol. The plausible mechanisms were proposed, in which RGO acted as a solid base catalyst and GO as a solid acid catalyst. (C) 2015 Elsevier Ltd. All rights reserved.