Visible-light-driven electrocyclization of activated allylic amines via azomethine ylide formation

摘要

Visible-light-driven aerobic oxidative 6 pi-electrocylization of tetrahydroisoquinoline (THIQ) derived activated allylic amines leading to functionalized tricyclic N-heterocycles is reported. The reaction proceeds through visible-light-induced formation of the iminium ion followed by azomethine ylide generation, and cyclization steps. This is the first example of visible-light-initiated catalytic electrocyclization reaction at room temperature. (C) 2014 Elsevier Ltd. All rights reserved.