N-(Pyridin-2-yl)benzamide: efficient ligand for the nickel catalyzed Chan-Lam cross-coupling reaction

摘要

An efficient protocol for the Chan Lam cross-coupling reactions of arylboronic acids with aryl or alkyl amines has been developed by employing simple N-(pyridin-2-yl)benzamide ligand with Ni (OAc)(2)center dot 4H(2)O in the presence of TMG base. The reaction proceeded well with high yields by employing various N-nucleophiles at low catalytic loadings. (C) 2015 Elsevier Ltd. All rights reserved.