Chemoselective S_N2' reaction of nitroalkanes to dialkyl 2-(bromomethyl)fumarates under cetyltrimethylammonium hydroxide (CTAOH) catalysis

摘要

The chemoselective S_N2' reaction of a variety of primary nitroalkanes to dialkyl 2-(bromomethyl)fuma-rates can be efficiently performed under cetyltrimethylammonium hydroxide (CTAOH) catalysis. The α,β-unsaturated esters were obtained in satisfactory to good yields with the complete retention of the nitro group. KNitroalkanes;; CTAOH;; Chemoselective S_N2' reaction;; α,β-Unsaturated esters;; γ-Lactame