Copper-catalyzed direct thiolation of benzoxazole with diaryl disulfides and aryl thiols

摘要

The cross-coupling reaction of benzoxazole with aryl thiols using the CuI/2,2'-bipyridine complex as a catalyst in DMF at 80 °C under oxygen produced the corresponding aryl thioethers in moderate to good yields. The coupling reaction with diaryl disulfide also occurred under similar oxidative conditions.