Synthesis of pyridino[3 ',2 ': 4,5]pyrrolo[3,2-gipyrrolo-[3,4-e]indolizin-1,3-dione and pyrrolo[3,2-c]pyrazole skeletons

Anizon F; Pfeiffer B; Prudhomme M

首页> 外文期刊>Tetrahedron letters: The International Journal for the Rapid Publication of Preliminary Communications in Organic Chemistry >Synthesis of pyridino[3 ',2 ': 4,5]pyrrolo[3,2-gipyrrolo-[3,4-e]indolizin-1,3-dione and pyrrolo[3,2-c]pyrazole skeletons

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Synthesis of pyridino[3 ',2 ': 4,5]pyrrolo[3,2-gipyrrolo-[3,4-e]indolizin-1,3-dione and pyrrolo[3,2-c]pyrazole skeletons

机译：吡啶并[3'，2'：4,5]吡咯并[3,2-吡咯并-[3,4-e]吲哚并嗪-1,3-二酮和吡咯并[3,2-c]吡唑骨架的合成

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A three step synthesis of an isogranulatimide analogue, in which the imidazole moiety is replaced by a pyrrole unit and the indole heterocycle is replaced by a 7-azaindole moiety is described. Moreover, a novel synthetic pathway to the pyrrolo[3,2-c]pyrazole skeleton is reported. (c) 2005 Elsevier Ltd. All rights reserved.

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《Tetrahedron letters: The International Journal for the Rapid Publication of Preliminary Communications in Organic Chemistry》 |2006年第4期|共4页
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Anizon F; Pfeiffer B; Prudhomme M;
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isogranulatimide; antitumor agents; G2 checkpoint inhibitors; 7-azaindole; pyrrolo3; 2-cpyrazole; HETEROCYCLIC CYANINE DYES; CELL-CYCLE; IMIDAZOLE HETEROCYCLE; ISOGRANULATIMIDE; ANALOGS; CHK1; GRANULATIMIDE; CYCLIZATION; INHIBITION; MECHANISM;

机译：异烟酰胺;抗肿瘤药;G2检查点抑制剂;7-氮杂吲哚;吡咯并[3;2-c]吡唑;杂环花菁染料;细胞周期;咪唑杂环;异戊二烯酸酯;类似物;CHK1;GRATIMITIMIDE;环化;

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Synthesis of pyridino[3 ',2 ': 4,5]pyrrolo[3,2-gipyrrolo-[3,4-e]indolizin-1,3-dione and pyrrolo[3,2-c]pyrazole skeletons

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