Oxime esters of anthraquinone as photo-induced DNA-cleaving agents for single-and double-strand scissions

Jih Ru Hwu; Shwu-Chen Tsay; Shih Chin Hong; Yi-Jing Leu; Chih-Fen Liu; Shang-Shing P.Chou

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Oxime esters of anthraquinone as photo-induced DNA-cleaving agents for single-and double-strand scissions

机译：蒽醌的肟酯作为单链和双链剪接的光诱导DNA裂解剂

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Anthraquinone-O-9-(4-cyanobenzoyl)oxime (13) with binding ocnstant of 4.49 X 10~4 M~(-1) exhibited single-strand scission of DNA at the ocncentration of 10 muM and double-strand scission at 50 muM upon UV irradiation.

机译：结合常数为4.49 X 10〜4 M〜（-1）的蒽醌-O-9-（4-氰基苯甲酰基）肟（13）在10μM的浓度下表现出DNA的单链断裂，在50的浓度下表现出双链断裂。紫外线照射下的muM。

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《Tetrahedron letters: The International Journal for the Rapid Publication of Preliminary Communications in Organic Chemistry》 |2003年第l4期|共4页
作者
Jih Ru Hwu; Shwu-Chen Tsay; Shih Chin Hong; Yi-Jing Leu; Chih-Fen Liu; Shang-Shing P.Chou;
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正文语种 eng
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关键词
anthraquinone; DNA cleavage; photolysis; radicals;

机译：蒽醌;DNA切割;光解;自由基;

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1. Oxime esters of anthraquinone as photo-induced DNA-cleaving agents for single-and double-strand scissions [J] . Jih Ru Hwu, Shwu-Chen Tsay, Shih Chin Hong, Tetrahedron letters: The International Journal for the Rapid Publication of Preliminary Communications in Organic Chemistry . 2003,第l4期

机译：蒽醌的肟酯作为单链和双链剪接的光诱导DNA裂解剂
2. Oxime Esters of 2,6-Diazaanthracene-9,10-dione and 4,5-Diazafluoren-9-one as Photo-induced DNA-Cleaving Agents [J] . Molecules . 2012,第3期

机译：2,6-二氮杂蒽-9,10-二酮和4,5-二氮杂芴-9-的肟酯作为光诱导的DNA裂解剂
3. Photo-induced DNA cleavage by (heterocyclo)carbonyl oxime esters of anthraquinone [J] . Jih Ru Hwu, Jhih-Ren Yang, Shwu-Chen Tsay Tetrahedron letters: The International Journal for the Rapid Publication of Preliminary Communications in Organic Chemistry . 2008,第20期

机译：蒽醌的（杂环）羰基肟酯对光诱导的DNA裂解
4. Design, Synthesis and Anti-fungal Activity of the Oleanic Acid Oxime Esters and Oxime Ethers [C] . Hanqing Zhao, Minjie Zhou, Jianjun Zhang, Proceedings of 4th international symposium on pesticides and environmental safety amp; 5th pan Pacific confernce on pesticide science amp; 8th international workshop on crop protection chemistry and regulatory harmonization . 2012

机译：齐墩果酸肟酯和肟醚的设计，合成及抗真菌活性
5. Preparation and Properties of Photo-induced Antimicrobial Cellulose Nanocrystals: Modified by Anthraquinone-2-Carboxylic Acid [D] . Zhu, Yiwen 2017

机译：蒽醌-2-羧酸修饰的光诱导抗菌纤维素纳米晶体的制备与性能
6. Oxime Esters of 26-Diazaanthracene-910-dione and 45-Diazafluoren-9-one as Photo-induced DNA-Cleaving Agents [O] . Shang-Shing P. Chou, Jui-Chi Juan, Shwu-Chen Tsay, 2012

机译：26-二氮杂蒽-910-二酮和45-二氮杂芴-9-一的肟酯作为光诱导的DNA裂解剂
7. Oxime Esters of 2,6-Diazaanthracene-9,10-dione and 4,5-Diazafluoren-9-one as Photo-induced DNA-Cleaving Agents [O] . Shang-Shing P. Chou, Jui-Chi Juan, Shwu-Chen Tsay, 2012

机译：2,6-二氮杂蒽-9,10-二酮和4,5-二氮杂芴-9-一的肟酯作为光诱导的DNA裂解剂
8. Testing of thiol-terminated oligonucleotides as potential DNA-cleaving reagents [R] . Balhorn, R. , Mazrimas, J. 1996

机译：测试巯基封端的寡核苷酸作为潜在的DNa切割试剂

Oxime esters of anthraquinone as photo-induced DNA-cleaving agents for single-and double-strand scissions

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