Facile syntheses of D-mannose hexa-and nonasaccharides: the di-and trimer of the trisaccharide repeating unit of the cell-wall mannans of Epidermophyton fluoccosum, Trychophyton mentagrophytes, Microsporum canis and related species of Microporum

摘要

A highly efficient strategy for the preparation of D-mannose hexa-and nonsaccharides, the dimer and trimer of the #alpha#-D-Manp-(1->6)-[#alpha#-D-Manp-(1->2)-]D-Manp trisaccharide repeating unit of the cell-wall mannans from the fungi Epidermophyton floccosum, Trychophyton mentagrophytes. Microsporum canis, M. cookei and M. racemosum, has been developed using 1,2,6-tri-O-acetyl-3,4-di-O-benzoyl-#alpha#-D-mannoyranose (6) as the key synthon.