Solid-phase synthesis of a folate conjugate of a DNA binding polyamide

Sanjay K. Sharma; J. William Lown

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Solid-phase synthesis of a folate conjugate of a DNA binding polyamide

机译：DNA结合聚酰胺的叶酸共轭物的固相合成

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摘要

Solid-phase synthesis of a folate tripyrrolocarboxamide conjugate 8 of a DNA binding polyamide is described. The synthesis of a new building block monomer Boc-Py-[(CH_2)_3-NHFmoc] acid 3 is also reported.

机译：描述了DNA结合聚酰胺的叶酸三吡咯并羧酰胺共轭物8的固相合成。还报道了新的结构单元单体Boc-Py-[（CH_2）_3-NHFmoc]酸3的合成。

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《Tetrahedron letters: The International Journal for the Rapid Publication of Preliminary Communications in Organic Chemistry 》 |2002年第37期| 共3页
作者
Sanjay K. Sharma; J. William Lown;
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正文语种 eng
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关键词
DNA; polyamides; folic acid; solid-phase; conjugate;

机译：DNA;聚酰胺;叶酸;固相;结合物;

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专利

1. Solid-phase synthesis of a folate conjugate of a DNA binding polyamide [J] . Sanjay K. Sharma, J. William Lown Tetrahedron letters: The International Journal for the Rapid Publication of Preliminary Communications in Organic Chemistry . 2002 ,第37期

机译：DNA结合聚酰胺的叶酸共轭物的固相合成
2. Rapid solid-phase synthesis of DNA-binding pyrrole-imidazole polyamides. [J] . Krutzik PO, Chamberlin AR Bioorganic and Medicinal Chemistry Letters . 2002 ,第16期

机译：DNA结合的吡咯-咪唑聚酰胺的快速固相合成。
3. Solid-phase synthesis of amidine-substituted phenylbenzimidazoles and incorporation of this DNA binding and recognition motif into amino acid and peptide conjugates [J] . Matthew L. Garner, Taxiarchis M. Georgiadis, Jessica Bo Li Amino acids . 2014 ,第5期

机译：固相合成am取代的苯基苯并咪唑并将这种DNA结合和识别基序并入氨基酸和肽结合物中
4. FOLATE RECEPTOR MEDIATED INTRACELLULAR DELIVERY OF PROTEINS ANDNANOPARTICLES BY USING PLL-PEG-FOLATE CONJUGATE [C] . Sun Hwa Kim, Ki Woo Chun, Ji Hoon Jeong, Controlled Release Society 31st annual meeting transactions: abstracts . 2004

机译：叶酸受体介导的PLL-PEG-叶酸共轭物介导的蛋白质和纳米颗粒的细胞内递送
5. Synthesis and Biological Studies of DNA-Binding Cyclic Py-Im Polyamides. [D] . Li, Benjamin Chun Yeung. 2013

机译：DNA结合环状Py-Im聚酰胺的合成和生物学研究。
6. Influence of structural variation on nuclear localization of DNA-binding polyamide-fluorophore conjugates [O] . Benjamin S. Edelson, Timothy P. Best, Bogdan Olenyuk, 2004

机译：结构变异对DNA结合聚酰胺-荧光团结合物核定位的影响
7. Solid-phase synthesis and DNA binding studies of dichloroplatinum(II) conjugates of dicarba analogues of octreotide as a new anticancer drugs [O] . Barragán Flavia, Moreno Martínez Virtudes, Marchán Sancho Vicente 2013

机译：新型奥曲肽双卡巴类似物的二氯铂（II）结合物的固相合成和DNA结合研究

Solid-phase synthesis of a folate conjugate of a DNA binding polyamide

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