A dual-responsive supramolecular amphiphile based on cucurbit[7]uril/butyrylcholine host-guest molecular recognition

摘要

A host guest molecular recognition is reported between cucurbit[7]uril and butyrylcholine with the driving forces of hydrophobic and charge-dipole interactions. On the basis of this recognition, an enzyme- and photo-responsive supramolecular amphiphile is fabricated, which self-assembles into vesicles in aqueous solution. The assembly and disassembly of vesicles are successfully employed in stimuli triggered releases of doxorubicin hydrochloride. (C) 2016 Published by Elsevier Ltd.