Syriacin, a novel unusual sulfated ceramide glycoside from the freshwater sponge Ephydatia syriaca (Porifera, Demospongiae, Spongillidae)

摘要

Syriacin, a novel unusual sulfated ceramide glycoside with branched very-long-chain fatty acid, i.e., (all Z)-34S-methylhexatriaconta-5,9,12,15,18,21-hexaenoic acid, has been isolated from the freshwater sponge Ephydatia syriaca. Its structure was identified by means of extensive spectroscopic analysis (IR, UV, 2D NMR, MS, CD) and chemical degradation. Syriacin showed antifeeding activity against goldfish at natural concentration (similar to 10 mu g/ml). (c) 2006 Elsevier Ltd. All rights reserved.