COPPER BIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATE)–CATALYZED COUPLING OF SODIUM AZIDE WITH ARYL IODIDES/BORONIC ACIDS TO ARYL AZIDES OR ARYL AMINES

摘要

This work reports an efficient protocol for the coupling reaction of aryl iodides/boronic acids with sodium azide to aryl azides/amines in the presence of copper bis(2,2, 6,6-tetramethyl-3,5-heptanedionate) Cu(TMHD)2 catalyst. The Cu(TMHD)2 catalyst is a structurally well-defined, O-containing, air- and moisture-stable, transition-metal complex and works at mild reaction conditions. It was observed that aryl azides can be reduced further to corresponding aniline derivatives using the same catalyst under basic reaction conditions for a prolonged period.