Plasma D-Dimer and Incident Ischemic Stroke and Coronary Heart Disease The Atherosclerosis Risk in Communities Study

摘要

Background and Purpose Epidemiological studies have documented that plasma d-dimer, a fibrin degradation product, is a risk marker for coronary heart disease, but there is limited prospective evidence for stroke. Given that thrombosis is a key mechanism for many strokes, we studied whether d-dimer is a risk marker for ischemic stroke incidence in the Atherosclerosis Risk in Communities (ARIC) Study.