Longitudinal Relationship Between Cerebral Small-Vessel Disease and Cerebral Blood Flow The Second Manifestations of Arterial Disease-Magnetic Resonance Study

摘要

Background and Purpose-Cerebral small-vessel disease and cerebral blood flow (CBF) are interrelated. However, the direction of the relationship is unknown, and longitudinal studies are scarce. We investigated the longitudinal relationship between CBF and white matter hyperintensities (WMHs) and lacunes, as representatives of cerebral small-vessel disease, in patients with manifest arterial disease.