Copper-Catalyzed Cross-Coupling Reaction of Allyl Boron Ester with 1 degrees/2 degrees/3 degrees-Halogenated Alkanes

摘要

The cross-coupling reaction of allyl boron ester with 1 degrees/2 degrees/3 degrees-halogenated alkanes in the presence of copper has been developed for the first time, which provides a mild and efficient method for the construction of saturated C(sp(3))C(sp(3)) bonds. This protocol shows excellent compatibility with the nonactivated primary, secondary, and even tertiary halogenated alkanes under mild conditions.