Silver-Catalyzed Decarboxylative Alkynylation of alpha,alpha-Difluoroarylacetic Acids with Ethynylbenziodoxolone Reagents

摘要

A decarboxylating alkynylation of alpha,alpha-difluoroarylacetic acids with ethynylbenziodoxolone reagents is reported. AgNO3 serves as the catalyst and K2S2O8 as the oxidant. A series of functional groups were tolerated, and moderate to good yields were obtained.