Copper-Catalyzed Chan?Lam Coupling between Sulfonyl Azides and Boronic Acids at Room Temperature

摘要

A mild and efficient method for the synthesis of N-arylsulfonamides in the presence of 10 mol % of CuCl is demonstrated. The reaction proceeds readily at room temperature in an open flask using a variety of sulfonyl azides and boronic acids without any base, ligand, or additive.